ロード中...

Mutations Reducing In Vitro Susceptibility to Novel LpxC Inhibitors in Pseudomonas aeruginosa and Interplay of Efflux and Nonefflux Mechanisms

Upregulated expression of efflux pumps, lpxC target mutations, LpxC protein overexpression, and mutations in fabG were previously shown to mediate single-step resistance to the LpxC inhibitor CHIR-090 in P. aeruginosa. Single-step selection experiments using three recently described LpxC inhibitors...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Jones, Adriana K., Caughlan, Ruth E., Woods, Angela L., Uehara, Kyoko, Xie, Lili, Barnes, S. Whitney, Walker, John R., Thompson, Katherine V., Ranjitkar, Srijan, Lee, Patrick S., Dean, Charles R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187589/
https://ncbi.nlm.nih.gov/pubmed/31658970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01490-19
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!