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Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase

Knowledge of the molecular events in mitochondrial DNA (mtDNA) replication is crucial to understanding the origins of human disorders arising from mitochondrial dysfunction. Twinkle helicase is an essential component of mtDNA replication. Here, we employed atomic force microscopy imaging in air and...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Kaur, Parminder, Longley, Matthew J., Pan, Hai, Wang, Wendy, Countryman, Preston, Wang, Hong, Copeland, William C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2020
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186178/
https://ncbi.nlm.nih.gov/pubmed/32213598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012795
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