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Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase
Knowledge of the molecular events in mitochondrial DNA (mtDNA) replication is crucial to understanding the origins of human disorders arising from mitochondrial dysfunction. Twinkle helicase is an essential component of mtDNA replication. Here, we employed atomic force microscopy imaging in air and...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7186178/ https://ncbi.nlm.nih.gov/pubmed/32213598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012795 |
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