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Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase

Knowledge of the molecular events in mitochondrial DNA (mtDNA) replication is crucial to understanding the origins of human disorders arising from mitochondrial dysfunction. Twinkle helicase is an essential component of mtDNA replication. Here, we employed atomic force microscopy imaging in air and...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Kaur, Parminder, Longley, Matthew J., Pan, Hai, Wang, Wendy, Countryman, Preston, Wang, Hong, Copeland, William C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186178/
https://ncbi.nlm.nih.gov/pubmed/32213598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012795
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