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Human Mitochondrial DNA Helicase TWINKLE Is Both an Unwinding and Annealing Helicase
TWINKLE is a nucleus-encoded human mitochondrial (mt)DNA helicase. Point mutations in TWINKLE are associated with heritable neuromuscular diseases characterized by deletions in the mtDNA. To understand the biochemical basis of these diseases, it is important to define the roles of TWINKLE in mtDNA m...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340288/ https://ncbi.nlm.nih.gov/pubmed/22383523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.309468 |
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