Human tau pathology transmits glial tau aggregates in the absence of neuronal tau

Tauopathies are characterized by abnormal accumulation of tau protein in neurons and glia. In Alzheimer’s disease (AD), tau aggregates in neurons, while in corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP), tau also aggregates in astrocytes and oligodendrocytes. We previously...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Narasimhan, Sneha, Changolkar, Lakshmi, Riddle, Dawn M., Kats, Alexandra, Stieber, Anna, Weitzman, Sarah A., Zhang, Bin, Li, Zhiyong, Roberson, Erik D., Trojanowski, John Q., Lee, Virginia M.Y.
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2019
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041709/
https://ncbi.nlm.nih.gov/pubmed/31826239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190783
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