Human tau pathology transmits glial tau aggregates in the absence of neuronal tau

Tauopathies are characterized by abnormal accumulation of tau protein in neurons and glia. In Alzheimer’s disease (AD), tau aggregates in neurons, while in corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP), tau also aggregates in astrocytes and oligodendrocytes. We previously...

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Bibliografski detalji
Izdano u:J Exp Med
Glavni autori: Narasimhan, Sneha, Changolkar, Lakshmi, Riddle, Dawn M., Kats, Alexandra, Stieber, Anna, Weitzman, Sarah A., Zhang, Bin, Li, Zhiyong, Roberson, Erik D., Trojanowski, John Q., Lee, Virginia M.Y.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041709/
https://ncbi.nlm.nih.gov/pubmed/31826239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190783
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