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Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo

One hallmark of neurodegenerative diseases is the intracellular accumulation of hyperphosphorylated tau protein, a neuronal microtubule-associated protein, into structures known as neurofibrillary tangles. Tauopathies are heterogeneous neurodegenerative diseases caused by the misfolding of the tau p...

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Bibliografiske detaljer
Udgivet i:J Neuropathol Exp Neurol
Main Authors: Weitzman, Sarah A, Narasimhan, Sneha, He, Zhuohao, Changolkar, Lakshmi, McBride, Jennifer D, Zhang, Bin, Schellenberg, Gerard D, Trojanowski, John Q, Lee, Virginia M Y
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445034/
https://ncbi.nlm.nih.gov/pubmed/32838419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlaa086
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