Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain

Pathological tau aggregates occur in Alzheimer's disease (AD) and other neurodegenerative tauopathies. It is not clearly understood why tauopathies vary greatly in the neuroanatomical and histopathological patterns of tau aggregation, which contribute to clinical heterogeneity in these disorder...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Narasimhan, Sneha, Guo, Jing L., Changolkar, Lakshmi, Stieber, Anna, McBride, Jennifer D., Silva, Luisa V., He, Zhuohao, Zhang, Bin, Gathagan, Ronald J., Trojanowski, John Q., Lee, Virginia M.Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700423/
https://ncbi.nlm.nih.gov/pubmed/29054878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1230-17.2017
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