Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain

Pathological tau aggregates occur in Alzheimer's disease (AD) and other neurodegenerative tauopathies. It is not clearly understood why tauopathies vary greatly in the neuroanatomical and histopathological patterns of tau aggregation, which contribute to clinical heterogeneity in these disorder...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Narasimhan, Sneha, Guo, Jing L., Changolkar, Lakshmi, Stieber, Anna, McBride, Jennifer D., Silva, Luisa V., He, Zhuohao, Zhang, Bin, Gathagan, Ronald J., Trojanowski, John Q., Lee, Virginia M.Y.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2017
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700423/
https://ncbi.nlm.nih.gov/pubmed/29054878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1230-17.2017
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