Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain

Pathological tau aggregates occur in Alzheimer's disease (AD) and other neurodegenerative tauopathies. It is not clearly understood why tauopathies vary greatly in the neuroanatomical and histopathological patterns of tau aggregation, which contribute to clinical heterogeneity in these disorder...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Narasimhan, Sneha, Guo, Jing L., Changolkar, Lakshmi, Stieber, Anna, McBride, Jennifer D., Silva, Luisa V., He, Zhuohao, Zhang, Bin, Gathagan, Ronald J., Trojanowski, John Q., Lee, Virginia M.Y.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700423/
https://ncbi.nlm.nih.gov/pubmed/29054878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1230-17.2017
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