GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils

Neurodegenerative proteinopathies characterized by intracellular aggregates of tau proteins, termed tauopathies, include Alzheimer's disease (AD), frontotemporal lobar degeneration (FTLD) with tau pathology (FTLD-tau), and related disorders. Pathological tau proteins derived from human AD brain...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gibbons, Garrett S., Banks, Rachel A., Kim, Bumjin, Xu, Hong, Changolkar, Lakshmi, Leight, Susan N., Riddle, Dawn M., Li, Chi, Gathagan, Ronald J., Brown, Hannah J., Zhang, Bin, Trojanowski, John Q., Lee, Virginia M.-Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700428/
https://ncbi.nlm.nih.gov/pubmed/28986461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2393-17.2017
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