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Axonal Degeneration Induced by Targeted Expression of Mutant Human Tau in Oligodendrocytes of Transgenic Mice That Model Glial Tauopathies

Abundant filamentous tau inclusions in oligodendrocytes (OLGs) are hallmarks of neurodegenerative tauopathies, including sporadic corticobasal degeneration and hereditary frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17). However, mechanisms of neurodegeneration in these ta...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Higuchi, Makoto, Zhang, Bin, Forman, Mark S., Yoshiyama, Yasumasa, Trojanowski, John Q., Lee, Virginia M.-Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725712/
https://ncbi.nlm.nih.gov/pubmed/16221853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2691-05.2005
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