Retarded Axonal Transport of R406W Mutant Tau in Transgenic Mice with a Neurodegenerative Tauopathy

Intracellular accumulations of filamentous tau inclusions are neuropathological hallmarks of neurodegenerative diseases known as tauopathies. The discovery of multiple pathogenic tau gene mutations in many kindreds with familial frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Zhang, Bin, Higuchi, Makoto, Yoshiyama, Yasumasa, Ishihara, Takeshi, Forman, Mark S., Martinez, Dan, Joyce, Sonali, Trojanowski, John Q., Lee, Virginia M.-Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2004
Schlagworte:
Neurobiology of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729383/
https://ncbi.nlm.nih.gov/pubmed/15140937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0797-04.2004
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