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Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies

Diverse neurodegenerative disorders are characterized by deposition of tau fibrils composed of conformers (i.e. strains) unique to each illness. The development of tau imaging agents has enabled visualization of tau lesions in tauopathy patients, but the modes of their binding to different tau strai...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Brain
Κύριοι συγγραφείς: Ono, Maiko, Sahara, Naruhiko, Kumata, Katsushi, Ji, Bin, Ni, Ruiqing, Koga, Shunsuke, Dickson, Dennis W., Trojanowski, John Q., Lee, Virginia M-Y., Yoshida, Mari, Hozumi, Isao, Yoshiyama, Yasumasa, van Swieten, John C., Nordberg, Agneta, Suhara, Tetsuya, Zhang, Ming-Rong, Higuchi, Makoto
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837223/
https://ncbi.nlm.nih.gov/pubmed/28087578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aww339
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