Pathologic correlations of [F-18]-AV-1451 imaging in non-Alzheimer tauopathies

OBJECTIVE: Recent studies have shown that PET tracer AV-1451 exhibits high binding affinity for paired helical filament (PHF)-tau pathology in Alzheimer’s brains. However, the ability of this ligand to bind to tau lesions in other tauopathies remains controversial. Our goal was to examine the correl...

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Udgivet i:Ann Neurol
Main Authors: Marquié, Marta, Normandin, Marc D., Meltzer, Avery C., Chong, Michael Siao Tick, Andrea, Nicolas V., Antón-Fernández, Alejandro, Klunk, William E., Mathis, Chester A., Ikonomovic, Milos D., Debnath, Manik, Bien, Elizabeth A., Vanderburg, Charles R., Costantino, Isabel, Makaretz, Sara, DeVos, Sarah L., Oakley, Derek H., Gomperts, Stephen N., Growdon, John H., Domoto-Reilly, Kimiko, Lucente, Diane, Dickerson, Bradford C., Frosch, Matthew P., Hyman, Bradley T., Johnson, Keith A., Gómez-Isla, Teresa
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319193/
https://ncbi.nlm.nih.gov/pubmed/27997036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24844
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