Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson’s case

[F-18]-AV-1451 is a novel positron emission tomography (PET) tracer with high affinity to neurofibrillary tau pathology in Alzheimer’s disease (AD). PET studies have shown increased tracer retention in patients clinically diagnosed with dementia of AD type and mild cognitive impairment in regions th...

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Bibliografske podrobnosti
izdano v:Acta Neuropathol Commun
Main Authors: Marquié, Marta, Verwer, Eline E., Meltzer, Avery C., Kim, Sally Ji Who, Agüero, Cinthya, Gonzalez, Jose, Makaretz, Sara J., Siao Tick Chong, Michael, Ramanan, Prianca, Amaral, Ana C., Normandin, Marc D., Vanderburg, Charles R., Gomperts, Stephen N., Johnson, Keith A., Frosch, Matthew P., Gómez-Isla, Teresa
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648451/
https://ncbi.nlm.nih.gov/pubmed/29047416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0482-0
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