Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson’s case

[F-18]-AV-1451 is a novel positron emission tomography (PET) tracer with high affinity to neurofibrillary tau pathology in Alzheimer’s disease (AD). PET studies have shown increased tracer retention in patients clinically diagnosed with dementia of AD type and mild cognitive impairment in regions th...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol Commun
Autori principali: Marquié, Marta, Verwer, Eline E., Meltzer, Avery C., Kim, Sally Ji Who, Agüero, Cinthya, Gonzalez, Jose, Makaretz, Sara J., Siao Tick Chong, Michael, Ramanan, Prianca, Amaral, Ana C., Normandin, Marc D., Vanderburg, Charles R., Gomperts, Stephen N., Johnson, Keith A., Frosch, Matthew P., Gómez-Isla, Teresa
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648451/
https://ncbi.nlm.nih.gov/pubmed/29047416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0482-0
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