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Cryptic Sites in Tau Fibrils Explain the Preferential Binding of the AV-1451 PET Tracer toward Alzheimer’s Tauopathy
[Image: see text] Tauopathies are a subclass of neurodegenerative diseases characterized by an accumulation of microtubule binding tau fibrils in brain regions. Diseases such as Alzheimer’s (AD), chronic traumatic encephalopathy (CTE), Pick’s disease (PiD), and corticobasal degeneration (CBD) belong...
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| Gepubliceerd in: | ACS Chem Neurosci |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical Society
2021
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8291571/ https://ncbi.nlm.nih.gov/pubmed/34152739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00340 |
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