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Attenuated Neurodegenerative Disease Phenotype in Tau Transgenic Mouse Lacking Neurofilaments

Previous studies have shown that transgenic (Tg) mice overexpressing human tau protein develop filamentous tau aggregates in the CNS. The most abundant tau aggregates are found in spinal cord and brainstem in which they colocalize with neurofilaments (NFs) as spheroids in axons. To elucidate the rol...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ishihara, Takeshi, Higuchi, Makoto, Zhang, Bin, Yoshiyama, Yasumasa, Hong, Ming, Trojanowski, John Q., Lee, Virginia M.-Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763173/
https://ncbi.nlm.nih.gov/pubmed/11487626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-16-06026.2001
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