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Therapeutic strategies for tau mediated neurodegeneration
Based on the amyloid hypothesis, controlling β-amyloid protein (Aβ) accumulation is supposed to suppress downstream pathological events, tau accumulation, neurodegeneration and cognitive decline. However, in recent clinical trials, Aβ removal or reducing Aβ production has shown limited efficacy. Mor...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3912572/ https://ncbi.nlm.nih.gov/pubmed/23085937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2012-303144 |
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