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Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration

RNA-binding proteins, and in particular TAR DNA-binding protein 43 (TDP43), are central to the pathogenesis of motor neuron diseases and related neurodegenerative disorders. Studies on human tissue have implicated several possible mechanisms of disease and experimental studies are now attempting to...

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Hlavní autoři: Lee, Edward B., Lee, Virginia M.-Y., Trojanowski, John Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285250/
https://ncbi.nlm.nih.gov/pubmed/22127299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3121
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