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Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration
RNA-binding proteins, and in particular TAR DNA-binding protein 43 (TDP43), are central to the pathogenesis of motor neuron diseases and related neurodegenerative disorders. Studies on human tissue have implicated several possible mechanisms of disease and experimental studies are now attempting to...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285250/ https://ncbi.nlm.nih.gov/pubmed/22127299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3121 |
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