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Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration

RNA-binding proteins, and in particular TAR DNA-binding protein 43 (TDP43), are central to the pathogenesis of motor neuron diseases and related neurodegenerative disorders. Studies on human tissue have implicated several possible mechanisms of disease and experimental studies are now attempting to...

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Detalhes bibliográficos
Main Authors: Lee, Edward B., Lee, Virginia M.-Y., Trojanowski, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285250/
https://ncbi.nlm.nih.gov/pubmed/22127299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3121
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