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TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies

Given the critical role for TDP-43 in diverse neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP), there has been a recent surge in efforts to understand the normal functions of TDP-43 and the molecular basis of dysregulation that...

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Detalhes bibliográficos
Main Authors: Cohen, Todd J., Lee, Virginia M.Y., Trojanowski, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202652/
https://ncbi.nlm.nih.gov/pubmed/21783422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2011.06.004
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