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Evidence That Non-Fibrillar Tau Causes Pathology Linked To Neurodegeneration And Behavioral Impairments

The discovery that mutations within the tau gene lead to frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17) provided direct evidence that tau alterations can lead to neurodegenerative disease. While the presence of tau fibrils and tangles is a common feature of all tauopathi...

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Autores principales: Brunden, Kurt R., Trojanowski, John Q., Lee, Virginia M-Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789426/
https://ncbi.nlm.nih.gov/pubmed/18688089
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