Transgenic Mouse Model of Tau Pathology in Astrocytes Leading to Nervous System Degeneration

Filamentous tau inclusions in neurons and glia are neuropathological hallmarks of sporadic and familial tauopathies. Because tau gene mutations are pathogenic for the autosomal dominant tauopathy “frontotemporal dementia and parkinsonism linked to chromosome 17,” tau abnormalities are implicated dir...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Forman, Mark S., Lal, Devika, Zhang, Bin, Dabir, Deepa V., Swanson, Eric, Lee, Virginia M.-Y., Trojanowski, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725385/
https://ncbi.nlm.nih.gov/pubmed/15814784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0081-05.2005
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