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Transgenic Mouse Model of Tau Pathology in Astrocytes Leading to Nervous System Degeneration

Filamentous tau inclusions in neurons and glia are neuropathological hallmarks of sporadic and familial tauopathies. Because tau gene mutations are pathogenic for the autosomal dominant tauopathy “frontotemporal dementia and parkinsonism linked to chromosome 17,” tau abnormalities are implicated dir...

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Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Forman, Mark S., Lal, Devika, Zhang, Bin, Dabir, Deepa V., Swanson, Eric, Lee, Virginia M.-Y., Trojanowski, John Q.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725385/
https://ncbi.nlm.nih.gov/pubmed/15814784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0081-05.2005
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