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Detection of Alzheimer Disease (AD)-Specific Tau Pathology in AD and NonAD Tauopathies by Immunohistochemistry With Novel Conformation-Selective Tau Antibodies

Aggregation of tau into fibrillar structures within the CNS is a pathological hallmark of a clinically heterogeneous set of neurodegenerative diseases termed tauopathies. Unique misfolded conformations of tau, referred to as strains, are hypothesized to underlie the distinct neuroanatomical and cell...

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Detalles Bibliográficos
Publicado en:J Neuropathol Exp Neurol
Main Authors: Gibbons, Garrett S, Banks, Rachel A, Kim, Bumjin, Changolkar, Lakshmi, Riddle, Dawn M, Leight, Susan N, Irwin, David J, Trojanowski, John Q, Lee, Virginia M Y
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251598/
https://ncbi.nlm.nih.gov/pubmed/29415231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nly010
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