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Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies

We have recently shown acetylation of tau at lysine residue 280 (AC-K280) to be a disease-specific modification in Alzheimer disease (AD), corticobasal degeneration, and progressive supranuclear palsy, likely representing a major regulatory tau modification. Herein, we extend our observations using...

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Detalhes bibliográficos
Main Authors: Irwin, David J., Cohen, Todd J., Grossman, Murray, Arnold, Steven E., McCarty-Wood, Elisabeth, Van Deerlin, Vivianna M., Lee, Virginia M.-Y., Trojanowski, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730769/
https://ncbi.nlm.nih.gov/pubmed/23885714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.04.025
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