Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

The microtubule-binding protein, tau, is the major component of neurofibrillary inclusions characteristic of Alzheimer's disease and related neurodegenerative tauopathies. When tau fibrillizes, it undergoes abnormal post-translational modifications resulting in decreased solubility and altered...

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Main Authors: Irwin, David J., Cohen, Todd J., Grossman, Murray, Arnold, Steven E., Xie, Sharon X., Lee, Virginia M.-Y., Trojanowski, John Q.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2012
Ábhair:
Original Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286338/
https://ncbi.nlm.nih.gov/pubmed/22366796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws013
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