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Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
The microtubule-binding protein, tau, is the major component of neurofibrillary inclusions characteristic of Alzheimer's disease and related neurodegenerative tauopathies. When tau fibrillizes, it undergoes abnormal post-translational modifications resulting in decreased solubility and altered...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286338/ https://ncbi.nlm.nih.gov/pubmed/22366796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws013 |
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