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Neuropathological changes and cognitive deficits in rats transgenic for human mutant tau recapitulate human tauopathy

The assembly of tau protein into abnormal filaments and brain cell degeneration are characteristic of a number of human neurodegenerative diseases, including Alzheimer's disease and frontotemporal dementia and parkinsonism linked to chromosome 17. Several murine models have been generated to be...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Malcolm, Janice C., Breuillaud, Lionel, Do Carmo, Sonia, Hall, Hélène, Welikovitch, Lindsay A., Macdonald, Jennifer A., Goedert, Michel, Cuello, A. Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597947/
https://ncbi.nlm.nih.gov/pubmed/30905766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.03.018
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