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Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain
Chronic inflammation during Alzheimer’s disease (AD) is most often attributed to sustained microglial activation in response to amyloid-β (Aβ) plaque deposits and cell death. However, cytokine release and microgliosis are consistently observed in AD transgenic animal models devoid of such pathologie...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7104377/ https://ncbi.nlm.nih.gov/pubmed/32144141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914593117 |
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