Human tau pathology transmits glial tau aggregates in the absence of neuronal tau

Tauopathies are characterized by abnormal accumulation of tau protein in neurons and glia. In Alzheimer’s disease (AD), tau aggregates in neurons, while in corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP), tau also aggregates in astrocytes and oligodendrocytes. We previously...

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Vydáno v:J Exp Med
Hlavní autoři: Narasimhan, Sneha, Changolkar, Lakshmi, Riddle, Dawn M., Kats, Alexandra, Stieber, Anna, Weitzman, Sarah A., Zhang, Bin, Li, Zhiyong, Roberson, Erik D., Trojanowski, John Q., Lee, Virginia M.Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041709/
https://ncbi.nlm.nih.gov/pubmed/31826239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190783
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