Human tau pathology transmits glial tau aggregates in the absence of neuronal tau

Tauopathies are characterized by abnormal accumulation of tau protein in neurons and glia. In Alzheimer’s disease (AD), tau aggregates in neurons, while in corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP), tau also aggregates in astrocytes and oligodendrocytes. We previously...

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Udgivet i:J Exp Med
Main Authors: Narasimhan, Sneha, Changolkar, Lakshmi, Riddle, Dawn M., Kats, Alexandra, Stieber, Anna, Weitzman, Sarah A., Zhang, Bin, Li, Zhiyong, Roberson, Erik D., Trojanowski, John Q., Lee, Virginia M.Y.
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041709/
https://ncbi.nlm.nih.gov/pubmed/31826239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190783
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