Live Respiratory Syncytial Virus Attenuated by M2-2 Deletion and Stabilized Temperature Sensitivity Mutation 1030s Is a Promising Vaccine Candidate in Children

BACKGROUND: The safety and immunogenicity of live respiratory syncytial virus (RSV) candidate vaccine, LID/ΔM2-2/1030s, with deletion of RSV ribonucleic acid synthesis regulatory protein M2-2 and genetically stabilized temperature-sensitivity mutation 1030s in the RSV polymerase protein was evaluate...

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Opis bibliograficzny
Wydane w:J Infect Dis
Główni autorzy: McFarland, Elizabeth J, Karron, Ruth A, Muresan, Petronella, Cunningham, Coleen K, Libous, Jennifer, Perlowski, Charlotte, Thumar, Bhagvanji, Gnanashanmugam, Devasena, Moye, Jack, Schappell, Elizabeth, Barr, Emily, Rexroad, Vivian, Fearn, Laura, Spector, Stephen A, Aziz, Mariam, Cielo, Mikhaela, Beneri, Christy, Wiznia, Andrew, Luongo, Cindy, Collins, Peter, Buchholz, Ursula J
Format: Artigo
Język:Inglês
Wydane: Oxford University Press 2020
Hasła przedmiotowe:
Major Articles and Brief Reports
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996856/
https://ncbi.nlm.nih.gov/pubmed/31758177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz603
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