Live Respiratory Syncytial Virus (RSV) Vaccine Candidate Containing Stabilized Temperature-Sensitivity Mutations Is Highly Attenuated in RSV-Seronegative Infants and Children

BACKGROUND: Respiratory syncytial virus (RSV) is the most important viral cause of severe respiratory illness in young children and lacks a vaccine. RSV cold-passage/stabilized 2 (RSVcps2) is a modification of a previously evaluated vaccine candidate in which 2 major attenuating mutations have been...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Infect Dis
Hlavní autoři: Buchholz, Ursula J, Cunningham, Coleen K, Muresan, Petronella, Gnanashanmugam, Devasena, Sato, Paul, Siberry, George K, Rexroad, Vivian, Valentine, Megan, Perlowski, Charlotte, Schappell, Elizabeth, Thumar, Bhagvinji, Luongo, Cindy, Barr, Emily, Aziz, Mariam, Yogev, Ram, Spector, Stephen A, Collins, Peter L, McFarland, Elizabeth J, Karron, Ruth A
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894088/
https://ncbi.nlm.nih.gov/pubmed/29509929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy066
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky