Increased Genetic and Phenotypic Stability of a Promising Live-Attenuated Respiratory Syncytial Virus Vaccine Candidate by Reverse Genetics

Por Luongo, Cindy, Winter, Christine C., Collins, Peter L., Buchholz, Ursula J.
Publicado em 2012

Respiratory Syncytial Virus Modified by Deletions of the NS2 Gene and Amino Acid S1313 of the L Polymerase Protein Is a Temperature-Sensitive, Live-Attenuated Vaccine Candidate Tha...

Por Luongo, Cindy, Winter, Christine C., Collins, Peter L., Buchholz, Ursula J.
Publicado em 2013

Nonstructural Proteins 1 and 2 of Respiratory Syncytial Virus Suppress Maturation of Human Dendritic Cells

Por Munir, Shirin, Le Nouen, Cyril, Luongo, Cindy, Buchholz, Ursula J., Collins, Peter L., Bukreyev, Alexander
Publicado em 2008

Responses against a Subdominant CD8(+) T Cell Epitope Protect against Immunopathology Caused by a Dominant Epitope

Por Ruckwardt, Tracy J., Luongo, Cindy, Malloy, Allison M. W., Liu, Jie, Chen, Man, Collins, Peter L., Graham, Barney S.
Publicado em 2010

Codon Stabilization Analysis of the “248” Temperature Sensitive Mutation for Increased Phenotypic Stability of Respiratory Syncytial Virus Vaccine Candidates

Por Luongo, Cindy, Yang, Lijuan, Winter, Christine C., Spann, Kirsten M., Murphy, Brian R., Collins, Peter L., Buchholz, Ursula J.
Publicado em 2009

α-Fetoprotein Gene Delivery to the Nasal Epithelium of Nonhuman Primates by Human Parainfluenza Viral Vectors

Por Zhang, Liqun, Limberis, Maria P., Thompson, Catherine, Antunes, Marcelo B., Luongo, Cindy, Wilson, James M., Collins, Peter L., Pickles, Raymond J.
Publicado em 2010

RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction

Por Liesman, Rachael M., Buchholz, Ursula J., Luongo, Cindy L., Yang, Lijuan, Proia, Alan D., DeVincenzo, John P., Collins, Peter L., Pickles, Raymond J.
Publicado em 2014

Deletion of M2 Gene Open Reading Frames 1 and 2 of Human Metapneumovirus: Effects on RNA Synthesis, Attenuation, and Immunogenicity

Por Buchholz, Ursula J., Biacchesi, Stéphane, Pham, Quynh N., Tran, Kim C., Yang, Lijuan, Luongo, Cindy L., Skiadopoulos, Mario H., Murphy, Brian R., Collins, Peter L.
Publicado em 2005

Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization

Por Le Nouën, Cyril, Brock, Linda G., Luongo, Cindy, McCarty, Thomas, Yang, Lijuan, Mehedi, Masfique, Wimmer, Eckard, Mueller, Steffen, Collins, Peter L., Buchholz, Ursula J., DiNapoli, Joshua M.
Publicado no Proc Natl Acad Sci U S A (2014)

Alpha and Lambda Interferon Together Mediate Suppression of CD4 T Cells Induced by Respiratory Syncytial Virus

Por Chi, Bo, Dickensheets, Harold L., Spann, Kirsten M., Alston, Marc A., Luongo, Cindy, Dumoutier, Laure, Huang, Jiaying, Renauld, Jean-Christophe, Kotenko, Sergei V., Roederer, Mario, Beeler, Judy A., Donnelly, Raymond P., Collins, Peter L., Rabin, Ronald L.
Publicado em 2006

A Chimeric A2 Strain of Respiratory Syncytial Virus (RSV) with the Fusion Protein of RSV Strain Line 19 Exhibits Enhanced Viral Load, Mucus, and Airway Dysfunction

Por Moore, Martin L., Chi, Michael H., Luongo, Cindy, Lukacs, Nicholas W., Polosukhin, Vasiliy V., Huckabee, Matthew M., Newcomb, Dawn C., Buchholz, Ursula J., Crowe, James E., Goleniewska, Kasia, Williams, John V., Collins, Peter L., Peebles, R. Stokes
Publicado em 2009

Respiratory syncytial virus infection induces a subset of types I and III interferons in human dendritic cells

Por Hillyer, Philippa, Mane, Viraj P., Chen, Aaron, dos Santos, Maria B., Schramm, Lynnsie M., Shepard, Rachel E., Luongo, Cindy, Le Nouën, Cyril, Huang, Lei, Yan, Lihan, Buchholz, Ursula J., Jubin, Ronald G., Collins, Peter L., Rabin, Ronald L.
Publicado no Virology (2017)

Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure

Por Le Nouën, Cyril, McCarty, Thomas, Brown, Michael, Smith, Melissa Laird, Lleras, Roberto, Dolan, Michael A., Mehedi, Masfique, Yang, Lijuan, Luongo, Cindy, Liang, Bo, Munir, Shirin, DiNapoli, Joshua M., Mueller, Steffen, Wimmer, Eckard, Collins, Peter L., Buchholz, Ursula J.
Publicado no Proc Natl Acad Sci U S A (2017)

RSV604, a Novel Inhibitor of Respiratory Syncytial Virus Replication

Por Chapman, Joanna, Abbott, Elizabeth, Alber, Dagmar G., Baxter, Robert C., Bithell, Sian K., Henderson, Elisa A., Carter, Malcolm C., Chambers, Phil, Chubb, Ann, Cockerill, G. Stuart, Collins, Peter L., Dowdell, Verity C. L., Keegan, Sally J., Kelsey, Richard D., Lockyer, Michael J., Luongo, Cindy, Najarro, Pilar, Pickles, Raymond J., Simmonds, Mark, Taylor, Debbie, Tyms, Stan, Wilson, Lara J., Powell, Kenneth L.
Publicado em 2007