RSV604, a Novel Inhibitor of Respiratory Syncytial Virus Replication

Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infections worldwide, yet no effective vaccine or antiviral treatment is available. Here we report the discovery and initial development of RSV604, a novel benzodiazepine with submicromolar anti-RSV activity. It pr...

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Bibliographische Detailangaben
Hauptverfasser: Chapman, Joanna, Abbott, Elizabeth, Alber, Dagmar G., Baxter, Robert C., Bithell, Sian K., Henderson, Elisa A., Carter, Malcolm C., Chambers, Phil, Chubb, Ann, Cockerill, G. Stuart, Collins, Peter L., Dowdell, Verity C. L., Keegan, Sally J., Kelsey, Richard D., Lockyer, Michael J., Luongo, Cindy, Najarro, Pilar, Pickles, Raymond J., Simmonds, Mark, Taylor, Debbie, Tyms, Stan, Wilson, Lara J., Powell, Kenneth L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043207/
https://ncbi.nlm.nih.gov/pubmed/17576833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00211-07
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