RSV604, a Novel Inhibitor of Respiratory Syncytial Virus Replication

Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infections worldwide, yet no effective vaccine or antiviral treatment is available. Here we report the discovery and initial development of RSV604, a novel benzodiazepine with submicromolar anti-RSV activity. It pr...

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Bibliografiska uppgifter
Huvudupphovsmän: Chapman, Joanna, Abbott, Elizabeth, Alber, Dagmar G., Baxter, Robert C., Bithell, Sian K., Henderson, Elisa A., Carter, Malcolm C., Chambers, Phil, Chubb, Ann, Cockerill, G. Stuart, Collins, Peter L., Dowdell, Verity C. L., Keegan, Sally J., Kelsey, Richard D., Lockyer, Michael J., Luongo, Cindy, Najarro, Pilar, Pickles, Raymond J., Simmonds, Mark, Taylor, Debbie, Tyms, Stan, Wilson, Lara J., Powell, Kenneth L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043207/
https://ncbi.nlm.nih.gov/pubmed/17576833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00211-07
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