RSV604, a Novel Inhibitor of Respiratory Syncytial Virus Replication

Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infections worldwide, yet no effective vaccine or antiviral treatment is available. Here we report the discovery and initial development of RSV604, a novel benzodiazepine with submicromolar anti-RSV activity. It pr...

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Detalhes bibliográficos
Main Authors: Chapman, Joanna, Abbott, Elizabeth, Alber, Dagmar G., Baxter, Robert C., Bithell, Sian K., Henderson, Elisa A., Carter, Malcolm C., Chambers, Phil, Chubb, Ann, Cockerill, G. Stuart, Collins, Peter L., Dowdell, Verity C. L., Keegan, Sally J., Kelsey, Richard D., Lockyer, Michael J., Luongo, Cindy, Najarro, Pilar, Pickles, Raymond J., Simmonds, Mark, Taylor, Debbie, Tyms, Stan, Wilson, Lara J., Powell, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043207/
https://ncbi.nlm.nih.gov/pubmed/17576833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00211-07
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