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Live-Attenuated Respiratory Syncytial Virus Vaccine Candidate With Deletion of RNA Synthesis Regulatory Protein M2-2 is Highly Immunogenic in Children
BACKGROUND: Live respiratory syncytial virus (RSV) candidate vaccine LIDΔM2-2 is attenuated by deletion of the RSV RNA regulatory protein M2-2, resulting in upregulated viral gene transcription and antigen expression but reduced RNA replication. METHODS: RSV-seronegative children ages 6–24 months re...
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| Veröffentlicht in: | J Infect Dis |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5894092/ https://ncbi.nlm.nih.gov/pubmed/29509911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy040 |
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