Attenuation of Live Respiratory Syncytial Virus Vaccines Is Associated With Reductions in Levels of Nasal Cytokines

Background. Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract illness (LRTI) in children. Several promising live-attenuated RSV vaccines are in development. Defining additional markers of attenuation could enhance clinical trials. Methods. We used clinical data, virolog...

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Main Authors: Karron, Ruth A., Thumar, Bhagvanji, Schappell, Elizabeth, Buchholz, Ursula J., Collins, Peter L.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Major Articles and Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693589/
https://ncbi.nlm.nih.gov/pubmed/23482643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit089
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