טוען...

TCF-1-centered transcriptional network drives an effector versus exhausted CD8 T cell fate decision

TCF-1 is a key transcription factor in progenitor exhausted CD8 T cells (Tex). Moreover, this Tex cell subset mediates responses to PD-1 checkpoint pathway blockade. However, the role of the transcription factor TCF-1 in early fate decisions and initial generation of Tex cells is unclear. Single cel...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Immunity
Main Authors: Chen, Zeyu, Ji, Zhicheng, Ngiow, Shin Foong, Manne, Sasikanth, Cai, Zhangying, Huang, Alexander C., Johnson, John, Staupe, Ryan P., Bengsch, Bertram, Xu, Caiyue, Yu, Sixiang, Kurachi, Makoto, Herati, Ramin S., Vella, Laura A., Baxter, Amy E., Wu, Jennifer E., Khan, Omar, Beltra, Jean-Christophe, Giles, Josephine R., Stelekati, Erietta, McLane, Laura M., Lau, Chi Wai, Yang, Xiaolu, Berger, Shelley L., Vahedi, Golnaz, Ji, Hongkai, Wherry, E. John
פורמט: Artigo
שפה:Inglês
יצא לאור: 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943829/
https://ncbi.nlm.nih.gov/pubmed/31606264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.09.013
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!