טוען...
TCF-1-centered transcriptional network drives an effector versus exhausted CD8 T cell fate decision
TCF-1 is a key transcription factor in progenitor exhausted CD8 T cells (Tex). Moreover, this Tex cell subset mediates responses to PD-1 checkpoint pathway blockade. However, the role of the transcription factor TCF-1 in early fate decisions and initial generation of Tex cells is unclear. Single cel...
שמור ב:
| הוצא לאור ב: | Immunity |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6943829/ https://ncbi.nlm.nih.gov/pubmed/31606264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.09.013 |
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