MiR-150 regulates memory CD8 T cell differentiation via c-Myb

MicroRNAs play an important role in T cell responses. However, how microRNAs regulate CD8 T cell memory remains poorly defined. Here, we found that miR-150 negatively regulates CD8 T cell memory in vivo. Genetic deletion of miR-150 disrupted the balance between memory precursor and terminal effector...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Chen, Zeyu, Stelekati, Erietta, Kurachi, Makoto, Yu, Sixiang, Cai, Zhangying, Manne, Sasikanth, Khan, Omar, Yang, Xiaolu, Wherry, E. John
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611819/
https://ncbi.nlm.nih.gov/pubmed/28903040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.060
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