Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy

Fuchs Endothelial Corneal Dystrophy (FECD) is an age-related genetically complex disease characterized by increased oxidative DNA damage and progressive degeneration of corneal endothelial cells (HCEnCs). FECD has a greater incidence and advanced phenotype in women, suggesting a possible role of hor...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Free Radic Biol Med
Auteurs principaux: Miyajima, Taiga, Melangath, Geetha, Zhu, Shan, Deshpande, Neha, Vasanth, Shivakumar, Mondal, Bodhisattwa, Kumar, Varun, Chen, Yuming, Price, Marianne, Price, Francis, Rogan, Eleanor G., Zahid, Muhammad, Jurkunas, Ula
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939626/
https://ncbi.nlm.nih.gov/pubmed/31857234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.12.014
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires