Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected

Fuchs endothelial corneal dystrophy (FECD) is a leading cause of corneal endothelial (CE) degeneration resulting in impaired visual acuity. It is a genetically complex and age-related disorder, with higher incidence in females. In this study, we established a nongenetic FECD animal model based on th...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Liu, Cailing, Miyajima, Taiga, Melangath, Geetha, Miyai, Takashi, Vasanth, Shivakumar, Deshpande, Neha, Kumar, Varun, Ong Tone, Stephan, Gupta, Reena, Zhu, Shan, Vojnovic, Dijana, Chen, Yuming, Rogan, Eleanor G., Mondal, Bodhiswatta, Zahid, Muhammad, Jurkunas, Ula V.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955350/
https://ncbi.nlm.nih.gov/pubmed/31852820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912546116
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki