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Decline in DJ-1 and Decreased Nuclear Translocation of Nrf2 in Fuchs Endothelial Corneal Dystrophy

PURPOSE. This study sought to determine factors involved in nuclear factor erythroid 2–related factor 2 (Nrf2) regulation and their response to oxidative stress in Fuchs endothelial corneal dystrophy (FECD) and normal corneal endothelial cells (CECs). METHODS. FECD corneal buttons were obtained from...

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Hlavní autoři: Bitar, Maya S., Liu, Cailing, Ziaei, Alireza, Chen, Yuming, Schmedt, Thore, Jurkunas, Ula V.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428112/
https://ncbi.nlm.nih.gov/pubmed/22836768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10119
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