p53-Regulated Increase in Oxidative-Stress–Induced Apoptosis in Fuchs Endothelial Corneal Dystrophy: A Native Tissue Model

PURPOSE. This study compared susceptibility of Fuchs endothelial corneal dystrophy (FECD) and normal corneal endothelial cells (CECs) to oxidative stress, and studied the mechanism of oxidative-stress–induced apoptosis in FECD-affected endothelium. METHODS. For in vitro studies, immortalized normal...

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Main Authors: Azizi, Behrooz, Ziaei, Alireza, Fuchsluger, Thomas, Schmedt, Thore, Chen, Yuming, Jurkunas, Ula V.
Format: Artigo
Jezik:Inglês
Izdano: Association for Research in Vision and Ophthalmology, Inc. 2011
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250096/
https://ncbi.nlm.nih.gov/pubmed/22064994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8312
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