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p53-Regulated Increase in Oxidative-Stress–Induced Apoptosis in Fuchs Endothelial Corneal Dystrophy: A Native Tissue Model
PURPOSE. This study compared susceptibility of Fuchs endothelial corneal dystrophy (FECD) and normal corneal endothelial cells (CECs) to oxidative stress, and studied the mechanism of oxidative-stress–induced apoptosis in FECD-affected endothelium. METHODS. For in vitro studies, immortalized normal...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250096/ https://ncbi.nlm.nih.gov/pubmed/22064994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8312 |
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