Metabolic regulation and energy homeostasis through the primary cilium

Por Oh, Edwin C., Vasanth, Shivakumar, Katsanis, Nicholas
Publicado no Cell Metab (2014)

Mutations in AGBL1 Cause Dominant Late-Onset Fuchs Corneal Dystrophy and Alter Protein-Protein Interaction with TCF4

Por Riazuddin, S. Amer, Vasanth, Shivakumar, Katsanis, Nicholas, Gottsch, John D.
Publicado em 2013

Identification of Nuclear Localization, DNA Binding, and Transactivating Mechanisms of Krüppel-like Zinc Finger Protein Gli-Similar 2 (Glis2)

Por Vasanth, Shivakumar, ZeRuth, Gary, Kang, Hong Soon, Jetten, Anton M.
Publicado em 2011

Gli-Similar (Glis) Proteins: Their Mechanisms of Action, Physiological Functions, and Roles in Disease

Por Lichti-Kaiser, Kristin, ZeRuth, Gary, Kang, Hong Soon, Vasanth, Shivakumar, Jetten, Anton M.
Publicado em 2012

CTG18.1 Expansion in TCF4 increases likelihood of transplantation in Fuchs Corneal Dystrophy

Por Eghrari, Allen O., Vasanth, Shivakumar, Wang, Jiangxia, Vahedi, Farnoosh, Riazuddin, S. Amer, Gottsch, John D.
Publicado no Cornea (2017)

Identification of a novel TCF4 isoform in human corneal endothelium

Por Eghrari, Allen O., Vasanth, Shivakumar, Gapsis, Briana C., Bison, Henry, Jurkunas, Ula, Riazuddin, S. Amer, Gottsch, John D.
Publicado no Cornea (2018)

Polycystin-1 regulates STAT activity by a dual mechanism

Por Talbot, Jeffrey J., Shillingford, Jonathan M., Vasanth, Shivakumar, Doerr, Nicholas, Mukherjee, Sambuddho, Kinter, Mike T., Watnick, Terry, Weimbs, Thomas
Publicado em 2011

Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease

Por Kang, Hong Soon, ZeRuth, Gary, Lichti-Kaiser, Kristin, Vasanth, Shivakumar, Yin, Zhengyu, Kim, Yong-Sik, Jetten, Anton M.
Publicado em 2010

Expansion of CTG18.1 Trinucleotide Repeat in TCF4 Is a Potent Driver of Fuchs' Corneal Dystrophy

Por Vasanth, Shivakumar, Eghrari, Allen O., Gapsis, Briana C., Wang, Jiangxia, Haller, Nicolas F., Stark, Walter J., Katsanis, Nicholas, Riazuddin, S. Amer, Gottsch, John D.
Publicado no Invest Ophthalmol Vis Sci (2015)

NQO1 downregulation potentiates menadione-induced endothelial-mesenchymal transition during rosette formation in Fuchs endothelial corneal dystrophy

Por Katikireddy, Kishore Reddy, White, Tomas L., Miyajima, Taiga, Vasanth, Shivakumar, Raoof, Duna, Chen, Yuming, Price, Marianne O., Price, Francis W., Jurkunas, Ula V.
Publicado no Free Radic Biol Med (2017)

Activation of PINK1-Parkin–Mediated Mitophagy Degrades Mitochondrial Quality Control Proteins in Fuchs Endothelial Corneal Dystrophy

Por Miyai, Takashi, Vasanth, Shivakumar, Melangath, Geetha, Deshpande, Neha, Kumar, Varun, Benischke, Anne-Sophie, Chen, Yuming, Price, Marianne O., Price, Francis W., Jurkunas, Ula V.
Publicado no Am J Pathol (2019)

Generation and Proteome Profiling of PBMC-Originated, iPSC-Derived Corneal Endothelial Cells

Por Ali, Muhammad, Khan, Shahid Y., Vasanth, Shivakumar, Ahmed, Mariya R., Chen, Ruiqiang, Na, Chan Hyun, Thomson, Jason J., Qiu, Caihong, Gottsch, John D., Riazuddin, S. Amer
Publicado no Invest Ophthalmol Vis Sci (2018)

Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy

Por Benischke, Anne-Sophie, Vasanth, Shivakumar, Miyai, Takashi, Katikireddy, Kishore Reddy, White, Tomas, Chen, Yuming, Halilovic, Adna, Price, Marianne, Price, Francis, Liton, Paloma B., Jurkunas, Ula V.
Publicado no Sci Rep (2017)

Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy

Por Miyajima, Taiga, Melangath, Geetha, Zhu, Shan, Deshpande, Neha, Vasanth, Shivakumar, Mondal, Bodhisattwa, Kumar, Varun, Chen, Yuming, Price, Marianne, Price, Francis, Rogan, Eleanor G., Zahid, Muhammad, Jurkunas, Ula
Publicado no Free Radic Biol Med (2019)

Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected

Por Liu, Cailing, Miyajima, Taiga, Melangath, Geetha, Miyai, Takashi, Vasanth, Shivakumar, Deshpande, Neha, Kumar, Varun, Ong Tone, Stephan, Gupta, Reena, Zhu, Shan, Vojnovic, Dijana, Chen, Yuming, Rogan, Eleanor G., Mondal, Bodhiswatta, Zahid, Muhammad, Jurkunas, Ula V.
Publicado no Proc Natl Acad Sci U S A (2020)

Dosage Changes of a Segment at 17p13.1 Lead to Intellectual Disability and Microcephaly as a Result of Complex Genetic Interaction of Multiple Genes

Por Carvalho, Claudia M.B., Vasanth, Shivakumar, Shinawi, Marwan, Russell, Chad, Ramocki, Melissa B., Brown, Chester W., Graakjaer, Jesper, Skytte, Anne-Bine, Vianna-Morgante, Angela M., Krepischi, Ana C.V., Patel, Gayle S., Immken, LaDonna, Aleck, Kyrieckos, Lim, Cynthia, Cheung, Sau Wai, Rosenberg, Carla, Katsanis, Nicholas, Lupski, James R.
Publicado no Am J Hum Genet (2014)

FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1

Por Khan, Shahid Y., Vasanth, Shivakumar, Kabir, Firoz, Gottsch, John D., Khan, Arif O., Chaerkady, Raghothama, Lee, Mei-Chong W., Leitch, Carmen C., Ma, Zhiwei, Laux, Julie, Villasmil, Rafael, Khan, Shaheen N., Riazuddin, Sheikh, Akram, Javed, Cole, Robert N., Talbot, C. Conover, Pourmand, Nader, Zaghloul, Norann A., Hejtmancik, J. Fielding, Riazuddin, S. Amer
Publicado no Nat Commun (2016)