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Polycystin-1 regulates STAT activity by a dual mechanism
Mutations in polycystin-1 (PC1) lead to autosomal-dominant polycystic kidney disease (ADPKD), a leading cause of renal failure for which no treatment is available. PC1 is an integral membrane protein, which has been implicated in the regulation of multiple signaling pathways including the JAK/STAT p...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093515/ https://ncbi.nlm.nih.gov/pubmed/21518865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103816108 |
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