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Identification of targets of IL-13 and STAT6 signaling in polycystic kidney disease
Autosomal dominant polycystic kidney disease (ADPKD) is a life-threatening, highly prevalent monogenic disease caused by mutations in polycystin-1 (PC1) in 85% of patients. We have previously identified a COOH-terminal cleavage fragment of PC1, PC1-p30, which interacts with the transcription factor...
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| Publié dans: | Am J Physiol Renal Physiol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6087790/ https://ncbi.nlm.nih.gov/pubmed/29513071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00346.2017 |
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