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Identification of targets of IL-13 and STAT6 signaling in polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is a life-threatening, highly prevalent monogenic disease caused by mutations in polycystin-1 (PC1) in 85% of patients. We have previously identified a COOH-terminal cleavage fragment of PC1, PC1-p30, which interacts with the transcription factor...

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Опубликовано в: :Am J Physiol Renal Physiol
Главные авторы: Olsan, Erin E., West, Jonathan D., Torres, Jacob A., Doerr, Nicholas, Weimbs, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087790/
https://ncbi.nlm.nih.gov/pubmed/29513071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00346.2017
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