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STAT3 Signaling in Polycystic Kidney Disease

Mutations in the gene coding for the integral membrane protein polycystin-1 (PC1) are the cause of most cases of autosomal-dominant polycystic kidney disease (ADPKD), a very common disease that leads to kidney failure and currently lacks approved treatment. Recent work has revealed that PC1 can regu...

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Detalhes bibliográficos
Publicado no:Drug Discov Today Dis Mech
Main Authors: Weimbs, Thomas, Talbot, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624194/
https://ncbi.nlm.nih.gov/pubmed/26523147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddmec.2013.03.001
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