Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy

Human corneal endothelial cells (HCEnCs) are terminally differentiated cells that have limited regenerative potential. The large numbers of mitochondria in HCEnCs are critical for pump and barrier function required for corneal hydration and transparency. Fuchs Endothelial Corneal Dystrophy (FECD) is...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Benischke, Anne-Sophie, Vasanth, Shivakumar, Miyai, Takashi, Katikireddy, Kishore Reddy, White, Tomas, Chen, Yuming, Halilovic, Adna, Price, Marianne, Price, Francis, Liton, Paloma B., Jurkunas, Ula V.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532298/
https://ncbi.nlm.nih.gov/pubmed/28751712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06523-2
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы