NQO1 downregulation potentiates menadione-induced endothelial-mesenchymal transition during rosette formation in Fuchs endothelial corneal dystrophy

Fuchs endothelial corneal dystrophy (FECD) is a genetic and oxidative stress disorder of post-mitotic human corneal endothelial cells (HCEnCs), which normally exhibit hexagonal shape and form a compact monolayer compatible with normal corneal functioning and clear vision. FECD is associated with inc...

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Gepubliceerd in:Free Radic Biol Med
Hoofdauteurs: Katikireddy, Kishore Reddy, White, Tomas L., Miyajima, Taiga, Vasanth, Shivakumar, Raoof, Duna, Chen, Yuming, Price, Marianne O., Price, Francis W., Jurkunas, Ula V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815941/
https://ncbi.nlm.nih.gov/pubmed/29294389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.12.036
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