Engineered nanoparticles for systemic siRNA delivery to malignant brain tumours

Improved delivery materials are needed to enable siRNA transport across biological barriers, including the blood–brain barrier (BBB), to treat diseases like brain cancer. We engineered bioreducible nanoparticles for systemic siRNA delivery to patient-derived glioblastoma cells in an orthotopic mouse...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nanoscale
Egile Nagusiak: Karlsson, Johan, Rui, Yuan, Kozielski, Kristen L., Placone, Amanda L., Choi, Olivia, Tzeng, Stephany Y., Kim, Jayoung, Keyes, Jamal J., Bogorad, Max I., Gabrielson, Kathleen, Guerrero-Cazares, Hugo, Quiñones-Hinojosa, Alfredo, Searson, Peter C., Green, Jordan J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924015/
https://ncbi.nlm.nih.gov/pubmed/31612183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9nr04795f
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