Cancer-selective Nanoparticles for Combinatorial siRNA Delivery to Primary Human GBM in vitro and in vivo

Novel treatments for glioblastoma (GBM) are urgently needed, particularly those which can simultaneously target GBM cells’ ability to grow and migrate. Herein, we describe a synthetic, bioreducible, biodegradable polymer that can package and deliver hundreds of siRNA molecules into a single nanopart...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Biomaterials
Autors principals: Kozielski, Kristen L., Ruiz-Valls, Alejandro, Tzeng, Stephany Y., Guerrero-Cázares, Hugo, Rui, Yuan, Li, Yuxin, Vaughan, Hannah J., Gionet-Gonzales, Marissa, Vantucci, Casey, Kim, Jayoung, Schiapparelli, Paula, Al-Kharboosh, Rawan, Quiñones-Hmojosa, Alfredo, Green, Jordan J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7122460/
https://ncbi.nlm.nih.gov/pubmed/31026613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.04.020
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars