Cancer-selective Nanoparticles for Combinatorial siRNA Delivery to Primary Human GBM in vitro and in vivo

Novel treatments for glioblastoma (GBM) are urgently needed, particularly those which can simultaneously target GBM cells’ ability to grow and migrate. Herein, we describe a synthetic, bioreducible, biodegradable polymer that can package and deliver hundreds of siRNA molecules into a single nanopart...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Biomaterials
Päätekijät: Kozielski, Kristen L., Ruiz-Valls, Alejandro, Tzeng, Stephany Y., Guerrero-Cázares, Hugo, Rui, Yuan, Li, Yuxin, Vaughan, Hannah J., Gionet-Gonzales, Marissa, Vantucci, Casey, Kim, Jayoung, Schiapparelli, Paula, Al-Kharboosh, Rawan, Quiñones-Hmojosa, Alfredo, Green, Jordan J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7122460/
https://ncbi.nlm.nih.gov/pubmed/31026613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.04.020
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